Tissues Engineering and Regenerative Therapies Centre
Developing keyhole surgery that repairs and regenerates joints
The Arthritis UK Tissue Engineering and Regenerative Therapies Centre brings together clinicians and scientists from the fields of engineering, biology and material science across Cambridge, Aberdeen, York, Keele and Oswestry.
Current treatments for early osteoarthritis are usually limited to non-surgical options such as pain killers and physiotherapy. Patients undergo joint replacement operations once the disease has progressed to joint failure, which involves major surgery and has associated risks.
Research at this centre aims to regenerate bone and cartilage by using the patients’ own stem cells to repair joint damage caused by osteoarthritis.
This centre first opened in 2011 and was renewed for a second term in 2016. It is in its ‘Impact’ phase until 2028.
Arthritis UK Biomechanics and Bioengineering Research Centre Impact Report
For many years, we’ve known that mechanical loading and inflammation contribute to osteoarthritis but the biological processes that link these factors were unknown. The impact of joint injury and joint surgery on our biomechanics and biology, and subtleties in gait or alignment that could contribute to long-term disease, was also unclear. Until now.
Our research centres of excellence
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Biomechanics and Bioengineering Research Centre at Cardiff University
Under the leadership of Professors Duance, Caterson and Sparkes, the Arthritis UK Biomechanics and Bioengineering Research Centre has led a unique, interdisciplinary programme of research and translation aimed at helping people with musculoskeletal conditions live better.
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Centre for Sport, Exercise and Osteoarthritis
This centre brings together experts in sports medicine and osteoarthritis, to understand the relationship between exercise, sport, injury, rehabilitation and osteoarthritis.