Our research
As the world’s largest dedicated funder of arthritis research, we’re here to make sure everyone has access to the treatments and support they need to live the life they choose, with real hope of a cure in the future.
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Our research strategy
Arthritis UK's research strategy is driven by the needs of people with arthritis. That’s why it focusses on research with the greatest potential to improve the quality of life – translational research. Research that turns observations in the laboratory, clinic and community into interventions that directly improve the health of people living with arthritis.
Research we fund
A quick and accurate diagnosis is essential for people with arthritis - and so are personalised treatments that tackle arthritis before it does too much damage to the joints or other parts of the body. Our understanding of root causes and risk factors is growing. Explore our live research projects that are answering key research questions.
Arthritis UK research impact
Our research has helped us to make life-changing breakthroughs and improve the lives of millions of people with arthritis. Together, we've achieved so much, including funding centres of excellence.
Arthritis UK research news
We’ve all been told that knuckle cracking causes arthritis. But is that really true? Dr Donald Unger set out on a mission to see if cracking knuckles really causes arthritis.
Is cracking knuckles bad?Hope is on the horizon for lupus patients who don’t respond to current treatments, as major trial discovers a biomarker that holds real promise of a better future.
BEAT lupus clinical trialCertain types of exercise are not only safe for people with arthritis, but they can also be as effective in reducing pain as taking painkillers by reducing sensitisation.
Exercise and arthritis research
Arthritis UK's research achievements
Our research funded clinical trial that provided a new treatment option for uveitis and had a major impact on how young people with arthritis receive care. Together we've achieved so much, but there is still more to do. Find out more about our research breakthroughs.
Pain-relieving biologic drugs for inflammatory arthritis
Research funded by Arthritis UK led to the development of a new class of drugs, known as biologics, which have transformed the treatment of inflammatory arthritis and improved the lives of almost 2 million people worldwide. Biologic drugs, such as anti-TNF, trigger cells in the immune system called T cells to stop causing inflammation.
It’s 25 years since the first biologic anti-TNF drugs were approved and they have transformed inflammatory arthritis care. They are the result of years of painstaking research, trials and tests funded by Arthritis UK and The Kennedy Trust.
How does anti-TNF work?
Pain research
Find out how our Arthritis UK Pain Centre at the University of Nottingham has helped us understand what causes joint pain, why everybody’s pain is different, and discovered opportunities to better treat pain.
Arthritis UK Pain CentreThe Advanced pain discovery platform (APDP)is an exciting step forwards in pain research. It brings together experts from biological, psychosocial and cognitive pain research fields across the country.
Find out more about the APDPESCAPE-pain is a six-week programme offering ESCAPE-pain for knees and hips common in osteoarthritis and ESCAPE-pain for backs, designed to benefit people with chronic low back pain.
The ESCAPE-Pain programme
Pain and arthritis
Arthritis pain can have a severe impact on daily life, and current painkillers are often ineffective or cause unwanted side effects. One way to develop better treatments is to target the specific nerves responsible for joint pain.
‘The ultimate goal of my research is to identify which sensory nerve fibre types contribute to arthritis pain.’
Arthritis UK research centres of excellence
Arthritis UK research centres of excellence bring together leading scientists, clinicians, engineers and healthcare professionals from universities, hospitals and research institutions across the UK to tackle some of the biggest challenges in arthritis and musculoskeletal health.
Arthritis UK Biomechanics and Bioengineering Research Centre Impact Report
For many years, we’ve known that mechanical loading and inflammation contribute to osteoarthritis but the biological processes that link these factors were unknown. The impact of joint injury and joint surgery on our biomechanics and biology, and subtleties in gait or alignment that could contribute to long-term disease, was also unclear. Until now.
Arthritis UK Podcast: What is 'Plan B'?
Plan B is a groundbreaking plan to target the B cells responsible for so much arthritis pain. Listen on Spotify to these inspiring researchers, Professor Claudia Mauri, Professor David Isenberg and Dr Elizabeth Rosser, talk about their vital work.
Get involved in Arthritis UK research
People like you with lived experience of arthritis are key to bringing real life perspectives to help shape arthritis research. When you get involved in our research, you'll work in all our activities to ensure that the research we fund and support is of the highest quality and based on the needs of people with arthritis.
Ayo's story: How being a research partner "opened her eyes" to our work
After losing mobility in her legs, young mum, Ayo, was hospitalised in 2009 and needed oxygen to help her to breathe before being diagnosed with lupus. Since becoming a research partner, she supports the research team by reviewing applications for funding.
Be part of arthritis research
If you'd like to be part of a research study, search the NIHR (National Institute for Health and Care Research) Be Part of Research website to find projects near you.
Be Part of Research is a free service which makes it easy to find and take part in vital health and care research across the UK.
- Enter a town and click Search to narrow down your choices.
- Then click on Find studies now to see a list of projects available to you in that area.
- Read each study's details to find out who can take part and how and where to get involved.
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Created specially for people living with arthritis, every edition of Inspire magazine is packed with expert, in-depth research and lifestyle articles and features, covering what matters most to you — all for just £3 a month.