Live research projects
Rheumatoid arthritis - A new questionnaire for detecting central pain sensitisation in people
Learn more about a new questionnaire for detecting central pain sensitisation in people with rheumatoid arthritis.
Rheumatoid arthritis - Experimental Arthritis Treatment Centre - King's College London
Learn about our centre's aims to investigate new and better ways of diagnosing and treating patients with inflammatory arthritis and connective tissue diseases.
Rheumatoid arthritis - How do gut bacteria influence the development of RA
Learn about our research into how gut bacteria leads to the development of rheumatoid arthritis in people who are at risk of developing the condition.
Rheumatoid arthritis - A new way to switch off unwanted inflammation in rheumatoid arthritis
Read more about our research into neutrophils (a type of white blood cell) and a new way of switching off unwanted inflammation in rheumatoid arthritis.
Rheumatoid arthritis - Are bad stem cells responsible?
Learn about our research into testing the theory that RA is sustained and perpetuated by diseased stem cells in the joint that give rise to abnormal tissue.
Rheumatoid arthritis - Can an app improve mental and physical health support for people with arthritis?
Learn about our research into a new app which aims to explore mental and physical health support - providing personalised treatment for people with arthritis.
Rheumatoid arthritis - Can the differences in the microbiome be used to understand the effectiveness of drugs in rheumatoid arthritis?
Learn more about if the differences in the microbiome be used to understand the effectiveness of drugs in rheumatoid arthritis.
Rheumatoid arthritis - Can we personalise treatment for rheumatoid arthritis by looking at a patient’s immune cells in the blood?
Learn more can we personalise treatment for rheumatoid arthritis by looking at a patient’s immune cells in the blood?
Rheumatoid arthritis - Controlling inflammatory cells in rheumatoid arthritis
Learn about our research into how IRF5, a molecule that causes inflammation in rheumatoid arthritis, is controlled and identifying how it might be blocked.
Rheumatoid arthritis - Creating a computer model of immune cell function in inflammatory disease
Learn about our research into a computer model to predict which molecules activate the neutrophils (white blood cells), to prevent their damaging effects.
Rheumatoid arthritis - Defining the role of cell migration in the initiation and regulation of pathogenesis in inflammatory arthritis
Read more about defining the role of cell migration in the initiation and regulation of pathogenesis in inflammatory arthritis.
Rheumatoid arthritis - Designing a method for delivering drugs directly to the joint in rheumatoid arthritis
Learn more about our research into investigating a new method of drug delivery to observe its long term effects on the symptoms of rheumatoid arthritis.
Rheumatoid arthritis - Developing a device to monitor arthritis flare ups at home
Read about our research on developing a device to monitor arthritis flare ups at home.
Rheumatoid arthritis - Developing a new method to image blood vessel formation in rheumatoid arthritis
Learn more about our research into comparing ultrasound to a new, quicker imaging technique for assessing inflammation and predicting future joint damage.
Rheumatoid arthritis - Developing a wrist support for people with wrist and hand problems due to arthritis
Learn about our research project to produce a new, well designed wrist support for patients with wrist problems and to better inform health care professionals.
Rheumatoid arthritis - Developing new antibody-based treatments
Learn about our research into a new rheumatoid arthritis treatment based on antibodies that block the pro-inflammatory activity of a protein called tenascin-C.
Rheumatoid Arthritis - Developing new treatments to target FGF in people with rheumatoid arthritis who do not respond to other treatments
Read about our research on developing new treatments to target FGF in people with rheumatoid arthritis who do not respond to other treatments
Rheumatoid arthritis - Developing predictive and preventative approaches to rheumatoid arthritis
Learn about our research into predicting and preventing rheumatoid arthritis - from the views of patients, relatives, carers, and healthcare professionals.
Rheumatoid arthritis - Do gut bacteria influence immunity and rheumatoid arthritis?
Learn about our research into gut bacteria - its influence on developing RA and how differences can be correlated with features of the patients' immune cells.
Rheumatoid arthritis - Does steroid production in patients with rheumatoid arthritis cause joint destruction, muscle wasting and bone loss?
Learn more about does steroid production in patients with rheumatoid arthritis cause joint destruction, muscle wasting and bone loss?
Rheumatoid arthritis - Evaluation of specialised splinting software to support design for 3D printed wrist splints
Learn about our research into creating and evaluating computer design software to enable virtual splint design in preparation for 3D printing, for OA and RA.
Rheumatoid arthritis - Experimental Arthritis Treatment Centre - Cardiff
Read more about our centre which aims to improve the outcome of rheumatoid and psoriatic arthritis management by developing and testing novel treatments.
Rheumatoid arthritis - Exploring the role of platelet cells in inflammation
Learn about our research into how platelet molecules (fragments of cells that help blood to clot) regulate other molecules in the joint in rheumatoid arthritis.
Rheumatoid arthritis - Exploring three DNA areas associated with risk of developing rheumatoid arthritis
Learn about our research into the genes controlled by the three RA associated regions, the mechanism to control them and where the changes are important.
Rheumatoid arthritis - Finding behavioural and neural indicators of fatigue in inflammatory arthritis.
Learn about our research into patient's behavioural changes and biomarkers, which can be used to identify fatigue in individuals with inflammatory arthritis.
Rheumatoid arthritis - From bad to good: how anti-TNF therapy makes T-cells switch roles, from causing inflammation to reducing inflammation
Read more about how anti-TNF therapy makes T-cells switch roles, from causing inflammation to reducing inflammation.
Rheumatoid arthritis - How anti-inflammatory molecules are switched on
Learn about our research into discovering whether a molecule within white blood cells is key to activating the cells to produce anti-inflammatory chemicals.
Rheumatoid arthritis - How are rheumatoid arthritis symptoms linked to the body clock and the bacteria in the gut?
Read about our research, which aims to look at if rheumatoid arthritis symptoms and inflammation are linked to the body clock and how gut bacteria plays a role.
Rheumatoid Arthritis - How can digital support platforms assist people with rheumatoid arthritis increase physical activity levels?
Read about our research on how can digital support platforms assist people with rheumatoid arthritis increase physical activity levels.
Rheumatoid arthritis - How can we manipulate immune cells to treat arthritis?
Learn about our research into some important questions highlighted in clinical trials on the use of the dendritic cells (immune cells) as an immunotherapy.
Rheumatoid arthritis - How do certain types of immune cell protect against joint inflammation in rheumatoid arthritis?
Learn about our research into how a group of ‘protective’ macrophages may help to prevent inflammation and maintain joint re-mission in rheumatoid arthritis.
Rheumatoid arthritis - How do changes in the PTPN22 gene cause autoimmune disease?
Learn about our research into how a protein called Lyp, which is produced from the gene PTPN22, controls cell behaviour in ways that promote inflammation.
Rheumatoid arthritis - How do Omega-3 fats help to control inflammation in rheumatoid arthritis?
Learn about our research into how a lack of omega 3 can lead to the inability to switch off inflammation and if changing diet can stop persistent inflammation.
Rheumatoid arthritis - How does binding of antibodies to macrophages cause inflammation in autoimmune diseases?
Learn about our research into why the binding of an antibody to the macrophage cell changes the way it generates energy, producing toxins/inflammatory signals.
Rheumatoid arthritis - How does communication between different cells in the joint cause inflammation?
Learn about our research into how the communication between fibroblasts (cells in connective tissue) and macrophages (white blood cells) causes inflammation.
Rheumatoid arthritis - How does oral inflammation promote rheumatoid arthritis?
Learn about our research into whether inflammatory cells in periodontitis leads to disruption of the immune system - contributing to arthritis symptoms.
Rheumatoid arthritis - How small things matter: studying the role of microRNAs in rheumatoid arthritis
Learn about our research into whether microRNAs are important in the function and survival of specialised immune cells called monocytes in patients with RA.
Rheumatoid arthritis - Identifying new ways to treat rheumatoid arthritis
Learn about our research into how the matrix (a specialized network of molecules) drives inflammation and the benefit of targeting it in rheumatoid arthritis.
Rheumatoid arthritis - Implementing the MSK-HQ to empower patients and improve services
Learn about our research into useful ways of implementing the Musculoskeletal Health Questionnaire (MSK-HQ) into routine practice and assessing its value.
Rheumatoid arthritis - Improving understanding of the pain experienced in temporomandibular disorders
Learn about our research into whether a protein (TRPA1), found in joints, can be targeted to reduce the pain symptoms in temporomandibular disorders (TMDs).
Rheumatoid arthritis - Inhibiting blood vessels to stop the spread of inflammatory pain
Learn about our research into the link between continued pain in inflammatory arthritis, such as RA, and the activity in the blood vessels of the spinal cord.
Rheumatoid arthritis - Integrating innovative technologies for genotyping and phenotyping in stratified medicine
Learn about our Special Strategic Award in integrating innovative technologies for genotyping and phenotyping in stratified medicine for rheumatoid arthritis.
Rheumatoid arthritis - Investigating DNA changes to uncover rheumatoid arthritis risk
Learn about our research which aims to identify how genetic changes might increase the risk of developing rheumatoid arthritis - leading to better treatments.
Rheumatoid arthritis - Investigating factors that influence the severity of rheumatoid arthritis
Learn about our research which aims to investigate how the MICL molecule, found on the surface of cells of the immune system, influences rheumatoid arthritis.
Rheumatoid arthritis - Investigating how bacteria disrupts the immune system
Learn about our research into whether mouth and gut bacteria can trick the immune system to attack the body’s own tissues, causing rheumatoid arthritis.
Rheumatoid arthritis - Investigating how the nerve proteins HCN2 and AT2 contribute to pain in arthritis
Learn about our research into new mechanisms underlying the pain of arthritis, to identify new targets for the development of future pain relief drugs.
Rheumatoid arthritis - Investigating mechanisms of early disease that control inflammatory arthritis progression
Learn about our research into how germinal centres drive the disease process in early inflammatory arthritis and the potential IL-27 to predict and prevent.
Rheumatoid arthritis - Investigating stem cells in joint health and disease
Learn about our research in cutting-edge technologies to study the way the stem cells maintain normal joint tissues or become abnormal in joint diseases.
Rheumatoid arthritis - Investigating the impact of sleep patterns on the quality of life of people with rheumatoid arthritis.
Read more about investigating the impact of sleep patterns on the quality of life of people with rheumatoid arthritis.
Rheumatoid arthritis - Investigating the potential of drug delivery directly to damaged cartilage
Learn about our research into how microvesicles provide protection to cartilage and if they can be loaded with drugs to directly target damaged cartilage.
Rheumatoid arthritis - Investigating the role of the protein galactin-1 as an anti-inflammatory in rheumatoid arthritis
Read more about investigating the role of the protein galactin-1 as an anti-inflammatory in rheumatoid arthritis.
Rheumatoid arthritis - Looking at joint tissue to help understand sero-negative rheumatoid arthritis
Learn about our research aiming to further understand the development of sero-negative rheumatoid arthritis by looking at tissue from the affected joints.
Rheumatoid arthritis - Molecular ‘sulfation’ changes: a new pathway driving inflammation in rheumatoid arthritis?
Learn about our research into the effect of sulfation genes on inflammation and how they contribute to the persistent inflammation seen in rheumatoid arthritis.
Rheumatoid arthritis - Nurse and Allied Health Professional internship programme
Learn about our project for creating a network of rheumatology internships for health-care professionals in universities with outstanding clinical researchers.
Rheumatoid arthritis - Predicting the success of therapies for the treatment of rheumatoid arthritis
Learn about our research into identifying biological molecules, such as those found in the blood or joint tissue, used to predict a patient's response to drugs.
Rheumatoid arthritis - Reducing variation in care for people with rheumatoid arthritis
Learn about our research which aims to understand why there is a variation in care quality and treatment success between different rheumatology departments.
Rheumatoid arthritis - Stopping the development of harmful T-cells - a new approach to treating rheumatoid arthritis
Read more about stopping the development of harmful T-cells - a new approach to treating rheumatoid arthritis.
Rheumatoid arthritis - Studying immune cells to predict the onset and progression of rheumatoid arthritis, and predict response to JAK inhibitor medication.
Read about our research on studying immune cells to predict the onset and progression of rheumatoid arthritis, and predict response to JAK inhibitor medication.
Rheumatoid arthritis - Studying the interactions between different cells that can cause joint inflammation
Read about the interactions between different cells that can cause joint inflammation in rheumatoid arthritis.
Rheumatoid arthritis - Support for the Norfolk Arthritis Register (NOAR) as part of the Arthritis Research UK Centre for Epidemiology
Learn more about support for the Norfolk Arthritis Register (NOAR) as part of the Arthritis Research UK Centre for Epidemiology.
Rheumatoid arthritis - Switching off the pro-inflammatory state of immune cells
Learn about our research into the role of proteins in switching immune cells from pro-inflammatory to anti-inflammatory states in rheumatoid arthritis.
Rheumatoid arthritis - The quality of life impact of living with arthritis and other chronic conditions
Learn about our research investigating the additional conditions people with musculoskeletal conditions have and how they affect their quality of life.
Rheumatoid arthritis - The role of proteins in causing pain and inflammation in arthritis
Learn about our research aiming to test whether mediators (proteins), along with drugs that increase their levels, can promote healing in inflammatory cells.
Rheumatoid arthritis - UK Japan Pain, Action and Movement Network
Learn about our research project aiming to create a network between UK and Japanese neuroscientists and understand the relationship between movement and pain.
Rheumatoid arthritis - UK Research in Musculoskeletal Epidemiology
Learn about our Special Strategic Award at the University of Manchester for UK Research in Musculoskeletal Epidemiology (RIME) and rheumatoid arthritis.
Rheumatoid arthritis - Uncovering a role for TRPM2 ion channels in rheumatoid arthritis pain
Learn about our research into a protein called TRPM2, which is increased in cells found in the joint, and the role it plays in rheumatoid arthritis pain.
Rheumatoid arthritis - Understanding how cartilage damage is affected by newly discovered proteins
Learn about our research into correcting the damaging effect that enzymes have on joint tissue in many forms of arthritis, using recently discovered proteins.
Rheumatoid arthritis - Understanding how dying cells can either reduce or worsen inflammation
Learn about our research into the structure of the DNA of a dyeing cell, which causes inflammation, and how this information can be used to stop inflammation.
Rheumatoid arthritis - Understanding how Nav 1.7 proteins in nerves cause pain in arthritis
Learn about our research into understanding how NaVs (proteins) interact to create electrical signals in nerves, which result in pain in those with arthritis.
Rheumatoid arthritis - Understanding the role of dendritic integrins in autoimmunity
Learn about our research into determining the role of dendritic integrins (which control/coordinate the immune system) in the development of arthritic disease.
Rheumatoid arthritis - Understanding the role of gut bacteria and regulatory B cells in controlling rheumatoid arthritis and lupus
Read about understanding the role of gut bacteria and regulatory B cells in controlling rheumatoid arthritis and lupus.
Rheumatoid arthritis - Understanding the role of white blood cells in rheumatoid arthritis
Learn about our research which aims to further understand the role that a type of white blood cell, called neutrophils, play in joint damage and inflammation.
Rheumatoid arthritis - Understanding what causes changes to cells in inflamed joints
Learn about our research into why fibroblasts change their normal peaceful behaviour into an aggressive behaviour in patients with rheumatoid arthritis.
Rheumatoid arthritis - Understanding why pain persists when inflammation has resolved
Learn about our research which aims to understand how inflammation can lead to chronic pain that can persist long after the inflammation has resolved.
Rheumatoid arthritis - Using genetics to find novel drug targets for rheumatoid arthritis
Learn about our research which aims to understand how DNA changes affect genes and cause rheumatoid arthritis, using new methods where previous studies failed.
Rheumatoid arthritis - Using magnetic stimulation to understand how specific areas of the brain contribute to pain experienced in rheumatoid arthritis.
Learn more about using magnetic stimulation to understand how specific areas of the brain contribute to pain experienced in rheumatoid arthritis.
Rheumatoid arthritis - Utilising the circadian clock to open new treatment avenues for rheumatoid arthritis
Learn about our research into how the body clock regulates elements of the immune system to influence the inflammation underlying rheumatoid arthritis.
Rheumatoid arthritis - What causes the body to raise immune responses against its own cells in arthritis?
Learn about our research into the gene collections that control the activation of T-cells in autoimmune disease and revealing the mechanisms used to do this.
Rheumatoid arthritis - What information, skills and support do patients need to become 'activated' in their healthcare?
Read more about what information, skills and support do patients need to become 'activated' in their healthcare.
Rheumatoid arthritis - What is the best route for injecting tolerogenic dendritic cells into people with rheumatoid arthritis?
Read more about what is the best route for injecting tolerogenic dendritic cells into people with rheumatoid arthritis?
Rheumatoid arthritis - Why do certain rheumatoid arthritis patients display different forms of joint disease?
Learn about our research into how the diversity and severity of joint inflammation in different patients is controlled, which could lead to improving treatment.
Rheumatoid arthritis - WORKWELL: helping people with inflammatory arthritis to stay in work
Learn about our research into whether a work rehabilitation programme (WORKWELL) will improve the working lives of people with inflammatory arthritis.